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NIH - National Institutes of Health National Cancer Institute Division of Cancer Treatment and Diagnosis Center for Cancer Research
Developmental Therapeutics Clinic (DTC)
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Last Updated: 06/22/15

Overview For Patients

Located in Bethesda, Maryland, the DTC focuses on conducting clinical trials of new agents while providing exceptional clinical care to participants. Our mission is to lead groundbreaking research of new treatments for cancer. The clinic specializes in the development of new cancer treatments by understanding the way the treatments work in the cancer cells within the human body. The areas of research encompass all solid tumors, both common ones like breast, colon, and lung cancers as well as less common ones like liver and pancreatic cancers. In addition, the clinic specializes in rare tumors like alveolar soft part sarcoma, desmoid tumors, and BRCA-associated tumors. The DTC works with physicians and patients from all parts of the United States and occasionally the world.

The DTC conducts clinical trials to understand how new cancer treatments work to kill cancer cells. These studies may include first-in-human studies, specialized studies in rare tumor, and NCI-prioritized studies in personalized medicine. The clinic conducts a wide range of trials involving multiple ways to attack cancer cells. DTC investigators work with other experts within the NCI to better understand the results of treatments and the best ways to use treatments to get the most efficacious outcomes. Utilizing expertise in genetic development, DTC has is spearheading a trial in the NCI Personalized Medicine Initiative (MPACT). The researchers in DTC continuously search for new ways to understand the weaknesses of cancer cells so we can develop a better offense in the fight against cancer.

While the science and research is very important, the DTC staff’s ultimate goal is to offer patients treatment options, hope, and comfort. DTC clinicians, research nurses, and support staff have extensive experience both with these specialized early trials in cancer treatment and providing outstanding clinical care for patients with advanced malignancies.